Aromatisation of estradiol into testosterone is essential for normal sexual differentiation and production of viable gametes. In our previous studies some environmental pollutants inhibited aromatase activity 'in vitro' in catfish gonads. The proposed research intends to validate the findings 'in vivo' and to investigate to what extent the impact of those chemicals is ecologically relevant and may affect the reproductive output of exposed fish in natural environments.
aromatase inhibitor, clarias gariepinus, endocrine disruption, fish, in vitro toxicity, oryzias latipes, pollution
|Animal Ecology and Systematics Section||unknown|
created:2011-12-14 14:18:59 UTC, source:iweto